Institutions
Research Unit for Rare Diseases, First Faculty of Medicine at Charles University in Prague, General University Hospital and BIOCEV
The laboratory is focused on studying the molecular basis of rare genetically determined disorders. In its work combines latest techniques and methods of medical genomics, bioinformatics, metabolomics, molecular biology and biochemistry with detailed clinic-pathologic evaluation of the studied diseases. In recent years this approach led to identification of causal genes and characterization of molecular basis of more than a dozen of severe genetic diseases. The laboratory offers it's expertise to clinical centers both in the Czech Republic and abroad.
Department of Biology and Medical Genetics, Second Faculty of Medicine, Charles University and University Hospital Motol
Department of Biology and Medical Genetics is a clinical-diagnostic, academic and research institution. Main topics are diagnostics and further study of hereditary diseases in prenatal and postnatal phase of development by means of state of the art techniques of molecular genetics, molecular cytogenetics and next generation sequencing. By decision of Czech Ministry of Health a National coordination center for rare diseases was established at Department of Biology and Medical Genetics.
Masaryk University - CEITEC
CEITEC MU was established as a part of scientific centre of excellence Central European Institute of Technology (CEITEC). Shared Core Facility Genomics and Laboratory of Medical Genomics are based in newly built premises University Campus that offers high-end equipment and optimal conditions to solve current issues of biomedical and clinical research (from genome analysis, mapping of key genetic defects, molecular genetic diagnostics to search for suitable targets for gene therapy). The portfolio of services of shared Genomics laboratory includes high throughput massively parallel sequencing, cell separation using FACS and MACS, real time PCR including microfluidic PCR, microarrays and other technologies. Scientists from the Czech and foreign universities and research institutes interested in using the services of Genomics Laboratory can apply for financial support from the Ministry of Education, Youth and Sports (MEYS).
University Hospital Brno
Centre of molecular biology and gene therapy (CMBGT) forms a part of Department of Internal Medicine, Hematology and Oncology (IHOK) focused on research and development and is one of the key units of the University Hospital Brno. It deals with the molecular biological diagnostics in the field of haematooncology, solid tumors, inherited diseases and identification of pathogens in immunocompromised patients. It also applies cytometry and cytogenetic diagnostics in hematology and hematooncology an performs applied research in general field of human medicine.
Department of Medical Genetics, Faculty of Medicine in Pilsen, Charles University Prague and the University Hospital in Pilsen
Research activities of the group focus on the study of molecular markers of disorders of human reproduction, susceptibility to infectious diseases, oncogenesis and on the clinical aspects of broad group of rare genetic diseases.
Institute of Molecular and Translational Medicine,
Faculty of Medicine and Dentistry, Palacký University in Olomouc
The Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University in Olomouc is cutting-edge biomedical research institute in the Czech Republic. The IMTM’s mission is basic and translational biomedical research with the goal to understand the underlying causes of cancer and infectious diseases and to develop future human medicines and diagnostics.